Designation of Phenethyl Halides as List I Chemicals
Abstract
The Drug Enforcement Administration is proposing the control of phenethyl halides as list I chemicals under the Controlled Substances Act (CSA). Phenethyl halides are important to the illicit manufacture of fentanyl, as well as fentanyl analogues, and fentanyl- related substances as they are often used in synthetic routes to manufacture these substances. Further, in the respective synthetic routes in which they are used to manufacture fentanyl, fentanyl analogues, and fentanyl-related substances, various phenethyl halides, such as phenethyl bromide and phenethyl chloride, can be substituted for each other. If finalized, the proposed rule would subject handlers of phenethyl halides to the chemical regulatory provisions of the CSA and its implementing regulations. This proposed rulemaking does not establish a threshold for domestic and international transactions of phenethyl halides. As such, all transactions of phenethyl halides regardless of size or concentration, shall be regulated and would be subject to control under the CSA.
Federal Register Source
This document is published by the Office of the Federal Register, National Archives and Records Administration. Access the full regulatory text, preamble, and docket comments below.
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Frequently Asked Questions
What is the 2026-13825 Federal Register document?
Document 2026-13825 is a Proposed Rule published by the Department of Justice in the Federal Register on July 9, 2026. The Drug Enforcement Administration is proposing the control of phenethyl halides as list I chemicals under the Controlled Substances Act (CSA). Phenethyl halides are important to the illicit manufacture of fentanyl, as well as fentanyl analogues, and fentanyl- related substances as they are often used in synthetic routes to manufacture these substances. Further, in the respective synthetic routes in which they are used to manufacture fentanyl, fentanyl analogues, and fentanyl-related substances, various phenethyl halides, such as phenethyl bromide and phenethyl chloride, can be substituted for each other. If finalized, the proposed rule would subject handlers of phenethyl halides to the chemical regulatory provisions of the CSA and its implementing regulations. This proposed rulemaking does not establish a threshold for domestic and international transactions of phenethyl halides. As such, all transactions of phenethyl halides regardless of size or concentration, shall be regulated and would be subject to control under the CSA. View the original at https://www.federalregister.gov/documents/2026/07/09/2026-13825/designation-of-phenethyl-halides-as-list-i-chemicals.
Is document 2026-13825 an economically significant rule?
No. Document 2026-13825 is not classified as economically significant under Executive Order 12866. Economically significant rules require OIRA review and are estimated to have impacts of $100 million or more per year.