Specific Listing for Dipentylone, a Currently Controlled Schedule I Substance

Document 2025-15177 is a Final Rule published by the Department of Justice in the Federal Register on August 8, 2025, with an effective date of August 8, 2025. The Drug Enforcement Administration (DEA) is establishing a specific listing and DEA Controlled Substances Code Number (drug code) for 1-(1,3-benzodioxol-5-yl)-2-(dimethylamino)pentan-1-one (dipentylone; N,N-dimethylpentylone) in schedule I of the Controlled Substances Act (CSA). Although dipentylone is not specifically listed in schedule I of the CSA with its own unique drug code, it is a schedule I controlled substances in the United States because it is a positional isomer of N-ethylpenthylone (controlled August 31, 2018), which is a schedule I hallucinogen. Therefore, DEA is simply amending the schedule I hallucinogenic substances list in its regulations to separately include dipentylone. View the original at https://www.federalregister.gov/documents/2025/08/08/2025-15177/specific-listing-for-dipentylone-a-currently-controlled-schedule-i-substance.

No. Document 2025-15177 is not classified as economically significant under Executive Order 12866. Economically significant rules require OIRA review and are estimated to have impacts of $100 million or more per year.